Benefits | NatAxtin

A HARBinger of Health

Astaxanthin is a naturally-occurring molecule that has been vastly studied for the last 20 years, with more than 100 human clinical studies and 500 pre-clinical trials showing numerous benefits for the body.
 

The following list mentions some key findings of Astaxanthin's wide-ranging effects:

  • Higher count of immune T and B cells, improved performance of Natural Killer (NK) cells, and lower levels of DNA damage as well as pro-inflammatory proteins
    Park JS, Chyun JH, Kim YK, Line LL, Chew BP. Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutr Metab (Lond). 2010.
     

  • Higher levels of defensive salivary antibody (SgIA) added to lower levels of neutrophils
    Baralic et al. Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. Evid Based Complement Alternat Med. 2015.
     

  • Reduction of oxidative stress marker, hexanoyl-lysine, in the saliva
    Yamada et al. Evaluation of therapeutic effects of astaxanthin on impairments in salivary secretion. J Clin Biochem Nutr. 2010.

  • Reduction in creatine kinase and aspartate aminotransferase, suggesting an attenuation of muscle damage after hard training
    Djordjevic et al. Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players. 
    J Sports Med Phys Fitness. 2012

     

  • Decrease of inflammatory response under high oxidative stress conditions
    Baralic et al. Effect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer Players. Evid Based Complement Alternat Med. 2015.
     

  • Reduced average heart rate at submaximal endurance intensities
    Talbott et al. Effect of Astaxanthin Supplementation on Cardiorespiratory Function in Runners. EC Nutrition. 2016

  • Lower lipid erythrocytes and plasma oxidation
    Nakagawa et al. Amyloid β-induced erythrocytic damage and its attenuation by carotenoids, FEBS Letters, 585. 2011.
     

  • Improvement of cognitive function
    Katagiri et al. Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function: a randomized, double-blind, placebo-controlled study. J. Clin. Biochem. Nutr. 2012.
     

  • Boost of global mood and improvement of negative mood state parameters
    Talbott et al. Effect of Astaxanthin supplementation on psychophysiological heart-brain axis dynamics in healthy subjects. Functional Foods in Health and Disease. 2019.

  • Inhibition of age-related skin deterioration and maintenance of skin conditions during seasonal changes
    Tominaga et al. Protective effects of astaxanthin on skin deterioration. J. Clin. Biochem. Nutr. 2017.
     

  • Enhancement of skin elasticity, moisture, and fine wrinkles
    Yamashita et al. The Effects of a Dietary Supplement Containing Astaxanthin on Skin Condition. Japanese society of carotenoid research. 2006.
     

  • Decrease of corneocyte desquamation and increase of lipid droplets size resulting in facial skin rejuvenation
    Chalyk et al. Continuous astaxanthin intake reduces oxidative stress and reverses age-related morphological changes of residual skin surface components in middle-aged volunteers. Nutr Res. 2017.

  • Improvement of eye accommodation and amelioration of accommodative fatigue
    Takahashi N, Kajita M: Effects of astaxanthin on accommodative recovery. Journal of Clinical Therapeutics and Medicine. 2005. 
     

  • Enhancement of choroidal blood flow
    Saito et al. Astaxanthin increases choroidal blood flow velocity. Graefes Arch Clin Exp Ophthalmol. 2012.
     

  • Amelioration of accommodation amplitude
    Nagaki et al. Effects of Astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers. J. trad. Med. 2002. 

  • Currently recommended doses of astaxanthin as a dietary supplement of 2–12 mg/day are 400-800 fold lower than the no-observed-adverse-effect-level (NOAEL)
    Stewart et al. Safety assessment of astaxanthin-rich microalgae biomass: Acute and subchronic toxicity studies in rats. Food and Chemical Toxicology. 2008.
     

  • No negative effects on blood chemistry or hematology and no subject report adverse experiences with a dose of 20 mg/day
    Satoh et al. Preliminary Clinical Evaluation of Toxicity and Efficacy of A New Astaxanthin-rich Haematococcus pluvialis Extract. J. Clin. Biochem. Nutr. 2009.

  • Reduction of LDL oxidation, inhibiting the inflammatory response
    Iwamoto et al. Inhibition of low-density lipoprotein oxidation by astaxanthin. J Atheroscler Thromb. 2000. 
     

  • Improved blood rheology
    Miyawaki et al. Effects of Astaxanthin on Human Blood Rheology. Clin. Biochem. 2008.
     

  • Improvement of serum lipid profile by increasing HDL and adiponectin levels, preventing cholesterol accumulation in the vascular wall
    Yoshida et al. Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis. 2010.

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